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BMCBI
2005
178views more  BMCBI 2005»
13 years 5 months ago
A quantization method based on threshold optimization for microarray short time series
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
Barbara Di Camillo, Fatima Sanchez-Cabo, Gianna To...
BMCBI
2008
126views more  BMCBI 2008»
13 years 5 months ago
Relating gene expression data on two-component systems to functional annotations in Escherichia coli
Background: Obtaining physiological insights from microarray experiments requires computational techniques that relate gene expression data to functional information. Traditionall...
Anne M. Denton, Jianfei Wu, Megan K. Townsend, Pre...
BMCBI
2007
197views more  BMCBI 2007»
13 years 5 months ago
Boolean networks using the chi-square test for inferring large-scale gene regulatory networks
Background: Boolean network (BN) modeling is a commonly used method for constructing gene regulatory networks from time series microarray data. However, its major drawback is that...
Haseong Kim, Jae K. Lee, Taesung Park
BMCBI
2011
13 years 9 days ago
A Platform for Processing Expression of Short Time Series (PESTS)
Background: Time course microarray profiles examine the expression of genes over a time domain. They are necessary in order to determine the complete set of genes that are dynamic...
Anshu Sinha, Marianthi Markatou
BMCBI
2008
166views more  BMCBI 2008»
13 years 5 months ago
Learning transcriptional regulatory networks from high throughput gene expression data using continuous three-way mutual informa
Background: Probability based statistical learning methods such as mutual information and Bayesian networks have emerged as a major category of tools for reverse engineering mecha...
Weijun Luo, Kurt D. Hankenson, Peter J. Woolf