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» Normalization for triple-target microarray experiments
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BMCBI
2004
108views more  BMCBI 2004»
13 years 4 months ago
Improving the scaling normalization for high-density oligonucleotide GeneChip expression microarrays
Background: Normalization is an important step for microarray data analysis to minimize biological and technical variations. Choosing a suitable approach can be critical. The defa...
Chao Lu
BMCBI
2005
116views more  BMCBI 2005»
13 years 4 months ago
Can Zipf's law be adapted to normalize microarrays?
Background: Normalization is the process of removing non-biological sources of variation between array experiments. Recent investigations of data in gene expression databases for ...
Timothy Lu, Christine M. Costello, Peter J. P. Cro...
BMCBI
2010
156views more  BMCBI 2010»
13 years 4 months ago
Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments
Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
James H. Bullard, Elizabeth Purdom, Kasper D. Hans...
BMCBI
2008
135views more  BMCBI 2008»
13 years 4 months ago
Using Generalized Procrustes Analysis (GPA) for normalization of cDNA microarray data
Background: Normalization is essential in dual-labelled microarray data analysis to remove nonbiological variations and systematic biases. Many normalization methods have been use...
Huiling Xiong, Dapeng Zhang, Christopher J. Martyn...
BMCBI
2004
106views more  BMCBI 2004»
13 years 4 months ago
Spotting effect in microarray experiments
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...
Tristan Mary-Huard, Jean-Jacques Daudin, Sté...