Background: We present a novel method of protein fold decoy discrimination using machine learning, more specifically using neural networks. Here, decoy discrimination is represent...
Motivation: Finding a good network null model for protein-protein interaction (PPI) networks is a fundamental issue. Such a model would provide insights into the interplay between...
Background:Receptors and scaffold proteins possess a number of distinct domains and bind multiple partners. A common problem in modeling signaling systems arises from a combinator...
Holger Conzelmann, Julio Saez-Rodriguez, Thomas Sa...
Background: Elucidating biological networks between proteins appears nowadays as one of the most important challenges in systems biology. Computational approaches to this problem ...
Pierre Geurts, Nizar Touleimat, Marie Dutreix, Flo...
Background: Several supervised and unsupervised learning tools are available to classify functional genomics data. However, relatively less attention has been given to exploratory...