Sciweavers

25 search results - page 5 / 5
» Oligomeric protein structure networks: insights into protein...
Sort
View
BMCBI
2008
138views more  BMCBI 2008»
13 years 5 months ago
Using neural networks and evolutionary information in decoy discrimination for protein tertiary structure prediction
Background: We present a novel method of protein fold decoy discrimination using machine learning, more specifically using neural networks. Here, decoy discrimination is represent...
Ching-Wai Tan, David T. Jones
BIOINFORMATICS
2008
172views more  BIOINFORMATICS 2008»
13 years 5 months ago
Fitting a geometric graph to a protein-protein interaction network
Motivation: Finding a good network null model for protein-protein interaction (PPI) networks is a fundamental issue. Such a model would provide insights into the interplay between...
Desmond J. Higham, Marija Rasajski, Natasa Przulj
BMCBI
2006
122views more  BMCBI 2006»
13 years 5 months ago
A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networks
Background:Receptors and scaffold proteins possess a number of distinct domains and bind multiple partners. A common problem in modeling signaling systems arises from a combinator...
Holger Conzelmann, Julio Saez-Rodriguez, Thomas Sa...
BMCBI
2007
154views more  BMCBI 2007»
13 years 5 months ago
Inferring biological networks with output kernel trees
Background: Elucidating biological networks between proteins appears nowadays as one of the most important challenges in systems biology. Computational approaches to this problem ...
Pierre Geurts, Nizar Touleimat, Marie Dutreix, Flo...
BMCBI
2005
161views more  BMCBI 2005»
13 years 5 months ago
Non-linear mapping for exploratory data analysis in functional genomics
Background: Several supervised and unsupervised learning tools are available to classify functional genomics data. However, relatively less attention has been given to exploratory...
Francisco Azuaje, Haiying Wang, Alban Chesneau