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» On Data and Visualization Models for Signaling Pathways
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CMSB
2003
Springer
13 years 9 months ago
An Overview of Data Models for the Analysis of Biochemical Pathways
Biochemical pathways such as metabolic, regulatory or signal tranduction pathways can be viewed as interconnected processes forming an intricate network of functional and physical...
Yves Deville, David Gilbert, Jacques van Helden, S...
RECOMB
2006
Springer
14 years 4 months ago
De Novo Signaling Pathway Predictions Based on Protein-Protein Interaction, Targeted Therapy and Protein Microarray Analysis
Abstract. Mapping intra-cellular signaling networks is a critical step in developing an understanding of and treatments for many devastating diseases. The predominant ways of disco...
Derek A. Ruths, Jen-Te Tseng, Luay Nakhleh, Prahla...
BMCBI
2005
109views more  BMCBI 2005»
13 years 4 months ago
Automation of gene assignments to metabolic pathways using high-throughput expression data
Background: Accurate assignment of genes to pathways is essential in order to understand the functional role of genes and to map the existing pathways in a given genome. Existing ...
Liviu Popescu, Golan Yona
BMCBI
2005
189views more  BMCBI 2005»
13 years 4 months ago
Quantitative inference of dynamic regulatory pathways via microarray data
Background: The cellular signaling pathway (network) is one of the main topics of organismic investigations. The intracellular interactions between genes in a signaling pathway ar...
Wen-Chieh Chang, Chang-Wei Li, Bor-Sen Chen
APVIS
2009
13 years 5 months ago
Visualization of signal transduction processes in the crowded environment of the cell
In this paper, we propose a stochastic simulation to model and analyze cellular signal transduction. The high number of objects in a simulation requires advanced visualization tec...
Martin Falk, Michael Klann, Matthias Reuss, Thomas...