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» On External Indices for Mixtures: Validating Mixtures of Gen...
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BMCBI
2007
149views more  BMCBI 2007»
13 years 5 months ago
Novel and simple transformation algorithm for combining microarray data sets
Background: With microarray technology, variability in experimental environments such as RNA sources, microarray production, or the use of different platforms, can cause bias. Suc...
Ki-Yeol Kim, Dong Hyuk Ki, Ha Jin Jeong, Hei-Cheul...
BMCBI
2006
142views more  BMCBI 2006»
13 years 5 months ago
PedGenie: an analysis approach for genetic association testing in extended pedigrees and genealogies of arbitrary size
Background: We present a general approach to perform association analyses in pedigrees of arbitrary size and structure, which also allows for a mixture of pedigree members and ind...
Kristina Allen-Brady, Jathine Wong, Nicola J. Camp
BMCBI
2010
176views more  BMCBI 2010»
13 years 2 months ago
Haplotype association analyses in resources of mixed structure using Monte Carlo testing
Background: Genomewide association studies have resulted in a great many genomic regions that are likely to harbor disease genes. Thorough interrogation of these specific regions ...
Ryan Abo, Jathine Wong, Alun Thomas, Nicola J. Cam...
BMCBI
2010
107views more  BMCBI 2010»
13 years 5 months ago
Conditional random pattern model for copy number aberration detection
Background: DNA copy number aberration (CNA) is very important in the pathogenesis of tumors and other diseases. For example, CNAs may result in suppression of anti-oncogenes and ...
Fuhai Li, Xiaobo Zhou, Wanting Huang, Chung-Che Ch...
ARTMED
2004
118views more  ARTMED 2004»
13 years 5 months ago
Bayesian fluorescence in situ hybridisation signal classification
Previous research has indicated the significance of accurate classification of fluorescence in situ hybridisation (FISH) signals for the detection of genetic abnormalities. Based ...
Boaz Lerner