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» On Matching Large Life Science Ontologies in Parallel
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CLADE
2008
IEEE
14 years 3 days ago
SWARM: a scientific workflow for supporting bayesian approaches to improve metabolic models
With the exponential growth of complete genome sequences, the analysis of these sequences is becoming a powerful approach to build genome-scale metabolic models. These models can ...
Xinghua Shi, Rick Stevens
GECCO
2006
Springer
132views Optimization» more  GECCO 2006»
13 years 9 months ago
The role of diverse populations in phylogenetic analysis
The most popular approaches for reconstructing phylogenetic trees attempt to solve NP-hard optimization criteria such as maximum parsimony (MP). Currently, the bestperforming heur...
Tiffani L. Williams, Marc L. Smith
BMCBI
2008
77views more  BMCBI 2008»
13 years 5 months ago
SeqAn An efficient, generic C++ library for sequence analysis
Background: The use of novel algorithmic techniques is pivotal to many important problems in life science. For example the sequencing of the human genome [1] would not have been p...
Andreas Döring, David Weese, Tobias Rausch, K...
BMCBI
2010
132views more  BMCBI 2010»
13 years 5 months ago
Data structures and compression algorithms for high-throughput sequencing technologies
Background: High-throughput sequencing (HTS) technologies play important roles in the life sciences by allowing the rapid parallel sequencing of very large numbers of relatively s...
Kenny Daily, Paul Rigor, Scott Christley, Xiaohui ...
BMCBI
2007
168views more  BMCBI 2007»
13 years 5 months ago
Advancing translational research with the Semantic Web
Background: A fundamental goal of the U.S. National Institute of Health (NIH) "Roadmap" is to strengthen Translational Research, defined as the movement of discoveries i...
Alan Ruttenberg, Tim Clark, William Bug, Matthias ...