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BMCBI
2006
107views more  BMCBI 2006»
13 years 5 months ago
A reinforced merging methodology for mapping unique peptide motifs in members of protein families
Background: Members of a protein family often have highly conserved sequences; most of these sequences carry identical biological functions and possess similar three-dimensional (...
Hao-Teng Chang, Tun-Wen Pai, Tan-Chi Fan, Bo-Han S...
JCB
2002
108views more  JCB 2002»
13 years 5 months ago
Fast and Accurate Phylogeny Reconstruction Algorithms Based on the Minimum-Evolution Principle
This paper investigates the standard ordinary least-squares version 24 and the balanced version 20 of the minimum evolution principle. For the standard version, we provide a greedy...
Richard Desper, Olivier Gascuel
BMCBI
2010
131views more  BMCBI 2010»
13 years 2 months ago
A two-step site and mRNA-level model for predicting microRNA targets
Background: Despite experiments showing that the number of microRNA (miRNA) target sites is critical for miRNA targeting, most existing methods focus on identifying individual miR...
Takaya Saito, Pål Sætrom