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» On the Design of Oligos for Gene Synthesis
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BMCBI
2006
117views more  BMCBI 2006»
13 years 5 months ago
Gene Designer: a synthetic biology tool for constructing artificial DNA segments
Background: Direct synthesis of genes is rapidly becoming the most efficient way to make functional genetic constructs and enables applications such as codon optimization, RNAi re...
Alan Villalobos, Jon E. Ness, Claes Gustafsson, Je...
BMCBI
2005
84views more  BMCBI 2005»
13 years 5 months ago
Information theory-based algorithm for in silico prediction of PCR products with whole genomic sequences as templates
Background: A new algorithm for assessing similarity between primer and template has been developed based on the hypothesis that annealing of primer to template is an information ...
Youfang Cao, Lianjie Wang, Kexue Xu, Chunhai Kou, ...
GECCO
2006
Springer
190views Optimization» more  GECCO 2006»
13 years 9 months ago
Design synthesis of microelectromechanical systems using genetic algorithms with component-based genotype representation
An automated design synthesis system based on a multi-objective genetic algorithm (MOGA) has been developed for the optimization of surface-micromachined MEMS devices. A hierarchi...
Ying Zhang, Raffi R. Kamalian, Alice M. Agogino, C...
GECCO
2005
Springer
131views Optimization» more  GECCO 2005»
13 years 10 months ago
Multipopulation cooperative coevolutionary programming (MCCP) to enhance design innovation
This paper describes the development of an evolutionary algorithm called Multipopulation Cooperative Coevolutionary Programming (MCCP) that extends Genetic Programming (GP) to sea...
Emily M. Zechman, S. Ranji Ranjithan
BMCBI
2011
13 years 9 days ago
Empirical Bayesian models for analysing molecular serotyping microarrays
Background: Microarrays offer great potential as a platform for molecular diagnostics, testing clinical samples for the presence of numerous biomarkers in highly multiplexed assay...
Richard Newton, Jason Hinds, Lorenz Wernisch