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BMCBI
2010
115views more  BMCBI 2010»
13 years 6 months ago
Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat l
Background: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
BMCBI
2010
112views more  BMCBI 2010»
13 years 6 months ago
A parameter-adaptive dynamic programming approach for inferring cophylogenies
Background: Coevolutionary systems like hosts and their parasites are commonly used model systems for evolutionary studies. Inferring the coevolutionary history based on given phy...
Daniel Merkle, Martin Middendorf, Nicolas Wieseke
BMCBI
2007
160views more  BMCBI 2007»
13 years 6 months ago
Identifying protein complexes directly from high-throughput TAP data with Markov random fields
Background: Predicting protein complexes from experimental data remains a challenge due to limited resolution and stochastic errors of high-throughput methods. Current algorithms ...
Wasinee Rungsarityotin, Roland Krause, Arno Sch&ou...
SIGMETRICS
2008
ACM
101views Hardware» more  SIGMETRICS 2008»
13 years 5 months ago
How to parameterize models with bursty workloads
Although recent advances in theory indicate that burstiness in the service time process can be handled effectively by queueing models (e.g., MAP queueing networks [2]), there is a...
Giuliano Casale, Ningfang Mi, Ludmila Cherkasova, ...
BMCBI
2004
169views more  BMCBI 2004»
13 years 5 months ago
A power law global error model for the identification of differentially expressed genes in microarray data
Background: High-density oligonucleotide microarray technology enables the discovery of genes that are transcriptionally modulated in different biological samples due to physiolog...
Norman Pavelka, Mattia Pelizzola, Caterina Vizzard...