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BMCBI
2006
122views more  BMCBI 2006»
13 years 5 months ago
A multivariate prediction model for microarray cross-hybridization
Background: Expression microarray analysis is one of the most popular molecular diagnostic techniques in the post-genomic era. However, this technique faces the fundamental proble...
Yian A. Chen, Cheng-Chung Chou, Xinghua Lu, Elizab...
BMCBI
2006
110views more  BMCBI 2006»
13 years 5 months ago
Modelling the network of cell cycle transcription factors in the yeast Saccharomyces cerevisiae
Background: Reverse-engineering regulatory networks is one of the central challenges for computational biology. Many techniques have been developed to accomplish this by utilizing...
Shawn Cokus, Sherri Rose, David Haynor, Niels Gr&o...
BMCBI
2005
127views more  BMCBI 2005»
13 years 5 months ago
Genomes are covered with ubiquitous 11 bp periodic patterns, the "class A flexible patterns"
Background: The genomes of prokaryotes and lower eukaryotes display a very strong 11 bp periodic bias in the distribution of their nucleotides. This bias is present throughout a g...
Etienne Larsabal, Antoine Danchin
JCNS
2000
86views more  JCNS 2000»
13 years 5 months ago
Computational Modeling of Orientation Tuning Dynamics in Monkey Primary Visual Cortex
In the primate visual pathway, orientation tuning of neurons is first observed in the primary visual cortex. The LGN cells that comprise the thalamic input to V1 are not orientati...
M. C. Pugh, Dario L. Ringach, Robert Shapley, M. J...
TMI
2002
248views more  TMI 2002»
13 years 5 months ago
Adaptive Elastic Segmentation of Brain MRI via Shape Model Guided Evolutionary Programming
This paper presents a fully automated segmentation method for medical images. The goal is to localize and parameterize a variety of types of structure in these images for subsequen...
Alain Pitiot, Arthur W. Toga, Paul M. Thompson