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» On the role of differentiation for resampling detection
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BMCBI
2006
143views more  BMCBI 2006»
13 years 5 months ago
Fast estimation of the difference between two PAM/JTT evolutionary distances in triplets of homologous sequences
Background: The estimation of the difference between two evolutionary distances within a triplet of homologs is a common operation that is used for example to determine which of t...
Christophe Dessimoz, Manuel Gil, Adrian Schneider,...
CORR
2010
Springer
112views Education» more  CORR 2010»
13 years 5 months ago
Cooperative Automated Worm Response and Detection Immune Algorithm
The role of T-cells within the immune system is to confirm and assess anomalous situations and then either respond to or tolerate the source of the effect. To illustrate how these ...
Jungwon Kim, William O. Wilson, Uwe Aickelin, Juli...
BMCBI
2007
134views more  BMCBI 2007»
13 years 5 months ago
A framework for significance analysis of gene expression data using dimension reduction methods
Background: The most popular methods for significance analysis on microarray data are well suited to find genes differentially expressed across predefined categories. However, ide...
Lars Halvor Gidskehaug, Endre Anderssen, Arnar Fla...
BMCBI
2006
216views more  BMCBI 2006»
13 years 5 months ago
Machine learning approaches to supporting the identification of photoreceptor-enriched genes based on expression data
Background: Retinal photoreceptors are highly specialised cells, which detect light and are central to mammalian vision. Many retinal diseases occur as a result of inherited dysfu...
Haiying Wang, Huiru Zheng, David Simpson, Francisc...
BMCBI
2005
106views more  BMCBI 2005»
13 years 5 months ago
A multistep bioinformatic approach detects putative regulatory elements in gene promoters
Background: Searching for approximate patterns in large promoter sequences frequently produces an exceedingly high numbers of results. Our aim was to exploit biological knowledge ...
Stefania Bortoluzzi, Alessandro Coppe, Andrea Biso...