A multiobjective combinatorial optimization (MOCO) formulation for the following location-routing problem in healthcare management is given: For a mobile healthcare facility, a cl...
Within the field of Criminology, an important challenge is to investigate the spatio-temporal dynamics of crime. Typical questions in this area are how the emergence of criminal h...
Background: The detection of small yet statistically significant differences in gene expression in spotted DNA microarray studies is an ongoing challenge. Meeting this challenge r...
Background: The amount of information stemming from proteomics experiments involving (multi dimensional) separation techniques, mass spectrometric analysis, and computational anal...
Background: DNA microarrays contain thousands of different probe sequences represented on their surface. These are designed in such a way that potential cross-hybridization reacti...