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BMCBI
2005
169views more  BMCBI 2005»
12 years 1 months ago
Genetic interaction motif finding by expectation maximization - a novel statistical model for inferring gene modules from synthe
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
Yan Qi 0003, Ping Ye, Joel S. Bader
BMCBI
2007
144views more  BMCBI 2007»
12 years 1 months ago
Accelerated search for biomolecular network models to interpret high-throughput experimental data
Background: The functions of human cells are carried out by biomolecular networks, which include proteins, genes, and regulatory sites within DNA that encode and control protein e...
Suman Datta, Bahrad A. Sokhansanj
KDD
2008
ACM
147views Data Mining» more  KDD 2008»
13 years 2 months ago
Extracting shared subspace for multi-label classification
Multi-label problems arise in various domains such as multitopic document categorization and protein function prediction. One natural way to deal with such problems is to construc...
Shuiwang Ji, Lei Tang, Shipeng Yu, Jieping Ye
GECCO
2008
Springer
179views Optimization» more  GECCO 2008»
12 years 3 months ago
Evolution of discrete gene regulatory models
Gene regulatory networks (GRNs) are complex control systems that govern the interaction of genes, which ultimately control cellular processes at the protein level. GRNs can be ted...
Afshin Esmaeili, Christian Jacob
BMCBI
2005
109views more  BMCBI 2005»
12 years 1 months ago
Automation of gene assignments to metabolic pathways using high-throughput expression data
Background: Accurate assignment of genes to pathways is essential in order to understand the functional role of genes and to map the existing pathways in a given genome. Existing ...
Liviu Popescu, Golan Yona
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