Sciweavers

Share
85 search results - page 1 / 17
» Optimization algorithms for functional deimmunization of the...
Sort
View
BMCBI
2010
116views more  BMCBI 2010»
11 years 11 months ago
Optimization algorithms for functional deimmunization of therapeutic proteins
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
Andrew S. Parker, Wei Zheng, Karl E. Griswold, Chr...
ISVC
2007
Springer
12 years 5 months ago
Integrative Geometric-Hashing Approaches to Binding Site Modeling and Ligand-Protein Interaction Prediction
Abstract. The function of a protein is dependent on whether and how it can interact with various ligands. Therefore, an accurate prediction of protein-ligand interactions is paramo...
Joanna Lipinski-Kruszka, Rahul Singh
LION
2009
Springer
112views Optimization» more  LION 2009»
12 years 6 months ago
A Graph-Based Semi-supervised Algorithm for Protein Function Prediction from Interaction Maps
Abstract. Protein function prediction represents a fundamental challenge in bioinformatics. The increasing availability of proteomics network data has enabled the development of se...
Valerio Freschi
TCAD
2010
133views more  TCAD 2010»
11 years 6 months ago
Defect-Tolerant Design and Optimization of a Digital Microfluidic Biochip for Protein Crystallization
Protein crystallization is a commonly used technique for protein analysis and subsequent drug design. It predicts the 3-D arrangement of the constituent amino acids, which in turn ...
Tao Xu, Krishnendu Chakrabarty, Vamsee K. Pamula
BMCBI
2010
132views more  BMCBI 2010»
11 years 11 months ago
Protein docking by Rotation-Based Uniform Sampling (RotBUS) with fast computing of intermolecular contact distance and residue d
Background: Protein-protein interactions are fundamental for the majority of cellular processes and their study is of enormous biotechnological and therapeutic interest. In recent...
Albert Solernou, Juan Fernández-Recio
books