Background: There is an increasing number of proteins with known structure but unknown function. Determining their function would have a significant impact on understanding diseas...
This paper presents a new approach to site-directed recombination, swapping combinations of selected discontiguous fragments from a source protein in place of corresponding fragmen...
Background: Protein-protein, protein-DNA and protein-RNA interactions are of central importance in biological systems. Quadrapole Time-of-flight (Q-TOF) mass spectrometry is a sen...
Yong Tang, Yingfeng Chen, Cheryl F. Lichti, Roger ...
A novel technique to search for functional modules in a protein-protein interaction network is presented. The network is represented by the adjacency matrix associated with the und...
Proteins are known to perform a biological function by interacting with other proteins or compounds. Since protein–protein interaction is intrinsic to most cellular processes, pr...