20 search results - page 2 / 4 » Optimization based automated curation of metabolic reconstru... |
BMCBI
2010
13 years 5 months ago
2010
Background: A key challenge in systems biology is the reconstruction of an organism's metabolic network from its genome sequence. One strategy for addressing this problem is ...
BMCBI
2006
13 years 5 months ago
2006
Background: Biochemically detailed stoichiometric matrices have now been reconstructed for various bacteria, yeast, and for the human cardiac mitochondrion based on genomic and pr...
BMCBI
2007
13 years 5 months ago
2007
Background: Current methods for the automated generation of genome-scale metabolic networks focus on genome annotation and preliminary biochemical reaction network assembly, but d...
BMCBI
2005
13 years 5 months ago
2005
Background: Accurate assignment of genes to pathways is essential in order to understand the functional role of genes and to map the existing pathways in a given genome. Existing ...
GECCO
2006
Springer
13 years 9 months ago
2006
Springer
The toxicity of an anticancer drug is cleared from the body by different processes, including saturable metabolic and nonsaturable renal-excretion pathways. According to the princ...