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» PANP - a New Method of Gene Detection on Oligonucleotide Exp...
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BMCBI
2010
132views more  BMCBI 2010»
13 years 5 months ago
Parallel multiplicity and error discovery rate (EDR) in microarray experiments
Background: In microarray gene expression profiling experiments, differentially expressed genes (DEGs) are detected from among tens of thousands of genes on an array using statist...
Wayne Wenzhong Xu, Clay J. Carter
BMCBI
2006
116views more  BMCBI 2006»
13 years 5 months ago
Cluster analysis for DNA methylation profiles having a detection threshold
Background: DNA methylation, a molecular feature used to investigate tumor heterogeneity, can be measured on many genomic regions using the MethyLight technology. Due to the combi...
Paul Marjoram, Jing Chang, Peter W. Laird, Kimberl...
BMCBI
2006
108views more  BMCBI 2006»
13 years 5 months ago
Probe set algorithms: is there a rational best bet?
Affymetrix microarrays have become a standard experimental platform for studies of mRNA expression profiling. Their success is due, in part, to the multiple oligonucleotide featur...
Jinwook Seo, Eric P. Hoffman
BMCBI
2008
120views more  BMCBI 2008»
13 years 5 months ago
Statistical issues in the analysis of Illumina data
Background: Illumina bead-based arrays are becoming increasingly popular due to their high degree of replication and reported high data quality. However, little attention has been...
Mark J. Dunning, Nuno L. Barbosa-Morais, Andy G. L...
GFKL
2004
Springer
137views Data Mining» more  GFKL 2004»
13 years 10 months ago
Density Estimation and Visualization for Data Containing Clusters of Unknown Structure
Abstract. A method for measuring the density of data sets that contain an unknown number of clusters of unknown sizes is proposed. This method, called Pareto Density Estimation (PD...
Alfred Ultsch