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» Pairwise statistical significance of local sequence alignmen...
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BMCBI
2006
94views more  BMCBI 2006»
13 years 4 months ago
Novel knowledge-based mean force potential at the profile level
Background: The development and testing of functions for the modeling of protein energetics is an important part of current research aimed at understanding protein structure and f...
Qiwen Dong, Xiaolong Wang, Lei Lin
MIAR
2010
IEEE
13 years 3 months ago
A Framework for 3D Analysis of Facial Morphology in Fetal Alcohol Syndrome
Abstract. Surface-based morphometry (SBM) is widely used in biomedical imaging and other domains to localize shape changes related to different conditions. This paper presents a co...
Jing Wan, Li Shen, Shiaofen Fang, Jason McLaughlin...
BMCBI
2005
152views more  BMCBI 2005»
13 years 4 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer
BMCBI
2010
229views more  BMCBI 2010»
13 years 4 months ago
Mocapy++ - A toolkit for inference and learning in dynamic Bayesian networks
Background: Mocapy++ is a toolkit for parameter learning and inference in dynamic Bayesian networks (DBNs). It supports a wide range of DBN architectures and probability distribut...
Martin Paluszewski, Thomas Hamelryck
BMCBI
2006
137views more  BMCBI 2006»
13 years 4 months ago
Bounded search for de novo identification of degenerate cis-regulatory elements
Background: The identification of statistically overrepresented sequences in the upstream regions of coregulated genes should theoretically permit the identification of potential ...
Jonathan M. Carlson, Arijit Chakravarty, Radhika S...