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IPPS
2008
IEEE
13 years 11 months ago
Parallelized preprocessing algorithms for high-density oligonucleotide arrays
Studies of gene expression using high-density oligonucleotide microarrays have become standard in a variety of biological contexts. The data recorded using the microarray techniqu...
Markus Schmidberger, Ulrich Mansmann
BMCBI
2006
174views more  BMCBI 2006»
13 years 5 months ago
CARAT: A novel method for allelic detection of DNA copy number changes using high density oligonucleotide arrays
Background: DNA copy number alterations are one of the main characteristics of the cancer cell karyotype and can contribute to the complex phenotype of these cells. These alterati...
Jing Huang, Wen Wei, Joyce Chen, Jane Zhang, Guoyi...
BMCBI
2007
130views more  BMCBI 2007»
13 years 4 months ago
Differential analysis for high density tiling microarray data
Background: High density oligonucleotide tiling arrays are an effective and powerful platform for conducting unbiased genome-wide studies. The ab initio probe selection method emp...
Srinka Ghosh, Heather A. Hirsch, Edward A. Sekinge...
TCBB
2008
113views more  TCBB 2008»
13 years 4 months ago
Efficient Algorithms for the Computational Design of Optimal Tiling Arrays
The representation of a genome by oligonucleotide probes is a prerequisite for the analysis of many of its basic properties, such as transcription factor binding sites, chromosomal...
Alexander Schliep, Roland Krause
BMCBI
2008
124views more  BMCBI 2008»
13 years 5 months ago
A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
Huanying Ge, Chao Cheng, Lei M. Li