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» Parameter Estimation of Kinetic Rates in Stochastic Reaction...
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JCB
2006
185views more  JCB 2006»
13 years 4 months ago
Bayesian Sequential Inference for Stochastic Kinetic Biochemical Network Models
As postgenomic biology becomes more predictive, the ability to infer rate parameters of genetic and biochemical networks will become increasingly important. In this paper, we expl...
Andrew Golightly, Darren J. Wilkinson
BMCBI
2006
117views more  BMCBI 2006»
13 years 5 months ago
A method for estimation of elasticities in metabolic networks using steady state and dynamic metabolomics data and linlog kineti
Background: Dynamic modeling of metabolic reaction networks under in vivo conditions is a crucial step in order to obtain a better understanding of the (dis)functioning of living ...
I. Emrah Nikerel, Wouter A. van Winden, Walter M. ...
CDC
2009
IEEE
133views Control Systems» more  CDC 2009»
13 years 9 months ago
Kinetic perturbations as robustness analysis tool for biochemical reaction networks
— Models of biochemical reaction networks can be decomposed into a stoichiometric part and a kinetic part. The stoichiometric part describes the structural mass flows while the ...
Steffen Waldherr, Frank Allgöwer, Elling W. J...
IJON
2006
112views more  IJON 2006»
13 years 5 months ago
Comparison of automated parameter estimation methods for neuronal signaling networks
This work is a suitability study of the different optimization methods for automated parameter estimation (fitting) in the context of neuronal signaling networks. The Gepasi simul...
Antti Pettinen, Olli Yli-Harja, Marja-Leena Linne