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EVOW
2008
Springer
13 years 7 months ago
Enhancing Parameter Estimation of Biochemical Networks by Exponentially Scaled Search Steps
A fundamental problem of modelling in Systems Biology is to precisely characterise quantitative parameters, which are hard to measure experimentally. For this reason, it is common ...
Hendrik Rohn, Bashar Ibrahim, Thorsten Lenser, Tho...
EVOW
2007
Springer
13 years 11 months ago
Modeling the Shoot Apical Meristem in A. thaliana : Parameter Estimation for Spatial Pattern Formation
Understanding the self-regulatory mechanisms controlling the spatial and temporal structure of multicellular organisms represents one of the major challenges in molecular biology. ...
Tim Hohm, Eckart Zitzler
CAINE
2007
13 years 6 months ago
Parameter Estimation via Analysis of Fuzzy Clusters (PEAF): An Algorithm to Estimate Parameters of Agent-Based Models
Biologically focused, agent-based models need many parameters in order to simulate system dynamics. It is often essential to explore the consequences of many parameter vectors bef...
Shahab Sheikh-Bahaei, C. Anthony Hunt
BMCBI
2006
175views more  BMCBI 2006»
13 years 5 months ago
Parameter estimation for stiff equations of biosystems using radial basis function networks
Background: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for par...
Yoshiya Matsubara, Shinichi Kikuchi, Masahiro Sugi...
GECCO
2008
Springer
179views Optimization» more  GECCO 2008»
13 years 6 months ago
Evolution of discrete gene regulatory models
Gene regulatory networks (GRNs) are complex control systems that govern the interaction of genes, which ultimately control cellular processes at the protein level. GRNs can be ted...
Afshin Esmaeili, Christian Jacob