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BMCBI
2005
119views more  BMCBI 2005»
13 years 5 months ago
The distance-profile representation and its application to detection of distantly related protein families
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Chin-Jen Ku, Golan Yona
JCB
2007
146views more  JCB 2007»
13 years 5 months ago
MSOAR: A High-Throughput Ortholog Assignment System Based on Genome Rearrangement
The assignment of orthologous genes between a pair of genomes is a fundamental and challenging problem in comparative genomics, since many computational methods for solving variou...
Zheng Fu, Xin Chen, Vladimir Vacic, Peng Nan, Yang...
JASIS
2000
143views more  JASIS 2000»
13 years 5 months ago
Discovering knowledge from noisy databases using genetic programming
s In data mining, we emphasize the need for learning from huge, incomplete and imperfect data sets (Fayyad et al. 1996, Frawley et al. 1991, Piatetsky-Shapiro and Frawley, 1991). T...
Man Leung Wong, Kwong-Sak Leung, Jack C. Y. Cheng
JCB
2002
108views more  JCB 2002»
13 years 5 months ago
Fast and Accurate Phylogeny Reconstruction Algorithms Based on the Minimum-Evolution Principle
This paper investigates the standard ordinary least-squares version 24 and the balanced version 20 of the minimum evolution principle. For the standard version, we provide a greedy...
Richard Desper, Olivier Gascuel