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BMCBI
2005
113views more  BMCBI 2005»
13 years 4 months ago
PentaPlot: A software tool for the illustration of genome mosaicism
Background: Dekapentagonal maps depict the phylogenetic relationships of five genomes in a visually appealing diagram and can be viewed as an alternative to a single evolutionary ...
Lutz Hamel, Olga Zhaxybayeva, J. Peter Gogarten
BMCBI
2011
12 years 8 months ago
A fast and accurate method to detect allelic genomic imbalances underlying mosaic rearrangements using SNP array data
Background: Mosaicism for copy number and copy neutral chromosomal rearrangements has been recently identified as a relatively common source of genetic variation in the normal pop...
Juan R. González, Benjamin Rodriguez-Santia...
BMCBI
2005
133views more  BMCBI 2005»
13 years 4 months ago
Systematic determination of the mosaic structure of bacterial genomes: species backbone versus strain-specific loops
Background: Public databases now contain multitude of complete bacterial genomes, including several genomes of the same species. The available data offers new opportunities to add...
Hélène Chiapello, I. Bourgait, F. So...
SCFBM
2008
119views more  SCFBM 2008»
13 years 4 months ago
Permutation - based statistical tests for multiple hypotheses
Background: Genomics and proteomics analyses regularly involve the simultaneous test of hundreds of hypotheses, either on numerical or categorical data. To correct for the occurre...
Anyela Camargo, Francisco Azuaje, Haiying Wang, Hu...
BMCBI
2010
148views more  BMCBI 2010»
13 years 4 months ago
Calling SNPs without a reference sequence
Background: The most common application for the next-generation sequencing technologies is resequencing, where short reads from the genome of an individual are aligned to a refere...
Aakrosh Ratan, Yu Zhang, Vanessa M. Hayes, Stephan...