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BMCBI
2004
97views more  BMCBI 2004»
13 years 4 months ago
Performance of a genetic algorithm for mass spectrometry proteomics
Background: Recently, mass spectrometry data have been mined using a genetic algorithm to produce discriminatory models that distinguish healthy individuals from those with cancer...
Neal O. Jeffries
BMCBI
2007
166views more  BMCBI 2007»
13 years 4 months ago
Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics
Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...
Xinning Jiang, Xiaogang Jiang, Guanghui Han, Mingl...
CSDA
2008
126views more  CSDA 2008»
13 years 4 months ago
A new genetic algorithm in proteomics: Feature selection for SELDI-TOF data
Mass spectrometry from clinical specimens is used in order to identify biomarkers in a diagnosis. Thus, a reliable method for both feature selection and classification is required...
Christelle Reynès, Robert Sabatier, Nicolas...
BMCBI
2010
152views more  BMCBI 2010»
13 years 4 months ago
A high-throughput de novo sequencing approach for shotgun proteomics using high-resolution tandem mass spectrometry
Background: High-resolution tandem mass spectra can now be readily acquired with hybrid instruments, such as LTQ-Orbitrap and LTQ-FT, in high-throughput shotgun proteomics workflo...
Chongle Pan, Byung-Hoon Park, William H. McDonald,...
GECCO
2007
Springer
165views Optimization» more  GECCO 2007»
13 years 10 months ago
Peptide detectability following ESI mass spectrometry: prediction using genetic programming
The accurate quantification of proteins is important in several areas of cell biology, biotechnology and medicine. Both relative and absolute quantification of proteins is often d...
David C. Wedge, Simon J. Gaskell, Simon J. Hubbard...