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» Phenotypic complexity and local variations in neutral degree
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BIOSYSTEMS
2007
54views more  BIOSYSTEMS 2007»
13 years 5 months ago
Phenotypic complexity and local variations in neutral degree
Per Kristian Lehre, Pauline C. Haddow
BMCBI
2006
169views more  BMCBI 2006»
13 years 5 months ago
Comparative analysis of haplotype association mapping algorithms
Background: Finding the genetic causes of quantitative traits is a complex and difficult task. Classical methods for mapping quantitative trail loci (QTL) in miceuse an F2 cross b...
Phillip McClurg, Mathew T. Pletcher, Tim Wiltshire...
BMCBI
2010
125views more  BMCBI 2010»
13 years 5 months ago
Haplotype allelic classes for detecting ongoing positive selection
Background: Natural selection eliminates detrimental and favors advantageous phenotypes. This process leaves characteristic signatures in underlying genomic segments that can be r...
Julie Hussin, Philippe Nadeau, Jean-Françoi...
BMCBI
2006
174views more  BMCBI 2006»
13 years 5 months ago
CARAT: A novel method for allelic detection of DNA copy number changes using high density oligonucleotide arrays
Background: DNA copy number alterations are one of the main characteristics of the cancer cell karyotype and can contribute to the complex phenotype of these cells. These alterati...
Jing Huang, Wen Wei, Joyce Chen, Jane Zhang, Guoyi...
BMCBI
2008
122views more  BMCBI 2008»
13 years 5 months ago
Generating samples for association studies based on HapMap data
Background: With the completion of the HapMap project, a variety of computational algorithms and tools have been proposed for haplotype inference, tag SNP selection and genome-wid...
Jing Li, Yixuan Chen