10 search results - page 1 / 2 » Phylogeny based discovery of regulatory elements |
BMCBI
2006
13 years 4 months ago
2006
Background: Algorithms that locate evolutionarily conserved sequences have become powerful tools for finding functional DNA elements, including transcription factor binding sites;...
BIOCOMP
2009
13 years 2 months ago
2009
- Identification and annotation of all the functional elements in the genome, including genes and regulatory sequences, is a fundamental challenge in genomics and computational bio...
BMCBI
2011
12 years 8 months ago
2011
Background: Current approaches for identifying transcriptional regulatory elements are mainly via the combination of two properties, the evolutionary conservation and the overrepr...
BMCBI
2005
13 years 4 months ago
2005
Background: Searching for approximate patterns in large promoter sequences frequently produces an exceedingly high numbers of results. Our aim was to exploit biological knowledge ...
BMCBI
2008
13 years 4 months ago
2008
Background: The detection of conserved motifs in promoters of orthologous genes (phylogenetic footprints) has become a common strategy to predict cis-acting regulatory elements. S...