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GCB
2005
Springer
75views Biometrics» more  GCB 2005»
13 years 10 months ago
Planning isotopomer measurements for estimation of metabolic fluxes
Ari Rantanen, Taneli Mielikäinen, Juho Rousu,...
CMSB
2003
Springer
13 years 10 months ago
A Method for Estimating Metabolic Fluxes from Incomplete Isotopomer Information
Metabolic flux estimation—the problem of finding out the rates of reactions in metabolic pathways—is an important problem area in the study of metabolism. The most accurate t...
Juho Rousu, Ari Rantanen, Hannu Maaheimo, Esa Pitk...
BMCBI
2008
129views more  BMCBI 2008»
13 years 5 months ago
An analytic and systematic framework for estimating metabolic flux ratios from 13C tracer experiments
Background: Metabolic fluxes provide invaluable insight on the integrated response of a cell to environmental stimuli or genetic modifications. Current computational methods for e...
Ari Rantanen, Juho Rousu, Paula Jouhten, Nicola Za...
BMCBI
2007
97views more  BMCBI 2007»
13 years 5 months ago
A procedure for the estimation over time of metabolic fluxes in scenarios where measurements are uncertain and/or insufficient
Background: An indirect approach is usually used to estimate the metabolic fluxes of an organism: couple the available measurements with known biological constraints (e.g. stoichi...
Francisco Llaneras, Jesús Picó
BMCBI
2008
150views more  BMCBI 2008»
13 years 5 months ago
13C labeling experiments at metabolic nonstationary conditions: An exploratory study
Background: Stimulus Response Experiments to unravel the regulatory properties of metabolic networks are becoming more and more popular. However, their ability to determine enzyme...
Sebastian Aljoscha Wahl, Katharina Nöh, Wolfg...