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» PoGO: Prediction of Gene Ontology terms for fungal proteins
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BIOINFORMATICS
2007
161views more  BIOINFORMATICS 2007»
13 years 5 months ago
Functional evaluation of domain-domain interactions and human protein interaction networks
: Large amounts of protein and domain interaction data are being produced by experimental high-throughput techniques and computational approaches. To gain insight into the value of...
Andreas Schlicker, Carola Huthmacher, Fidel Ram&ia...
BMCBI
2008
200views more  BMCBI 2008»
13 years 5 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
BMCBI
2004
144views more  BMCBI 2004»
13 years 5 months ago
GOtcha: a new method for prediction of protein function assessed by the annotation of seven genomes
Background: The function of a novel gene product is typically predicted by transitive assignment of annotation from similar sequences. We describe a novel method, GOtcha, for pred...
David M. A. Martin, Matthew Berriman, Geoffrey J. ...
MCS
2010
Springer
13 years 10 months ago
An Experimental Comparison of Hierarchical Bayes and True Path Rule Ensembles for Protein Function Prediction
Abstract. The computational genome-wide annotation of gene functions requires the prediction of hierarchically structured functional classes and can be formalized as a multiclass, ...
Matteo Re, Giorgio Valentini
NAR
2008
174views more  NAR 2008»
13 years 4 months ago
miRGator: an integrated system for functional annotation of microRNAs
MicroRNAs (miRNAs) constitute an important class of regulators that are involved in various cellular and disease processes. However, the functional significance of each miRNA is m...
Seungyoon Nam, Bumjin Kim, Seokmin Shin, Sanghyuk ...