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» Polymorphic typed defunctionalization
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BMCBI
2007
163views more  BMCBI 2007»
13 years 5 months ago
Strainer: software for analysis of population variation in community genomic datasets
Background: Metagenomic analyses of microbial communities that are comprehensive enough to provide multiple samples of most loci in the genomes of the dominant organism types will...
John M. Eppley, Gene W. Tyson, Wayne M. Getz, Jill...
BMCBI
2007
129views more  BMCBI 2007»
13 years 5 months ago
A novel approach to sequence validating protein expression clones with automated decision making
Background: Whereas the molecular assembly of protein expression clones is readily automated and routinely accomplished in high throughput, sequence verification of these clones i...
Elena Taycher, Andreas Rolfs, Yanhui Hu, Dongmei Z...
BMCBI
2005
163views more  BMCBI 2005»
13 years 5 months ago
CoaSim: A flexible environment for simulating genetic data under coalescent models
Background: Coalescent simulations are playing a large role in interpreting large scale intraspecific sequence or polymorphism surveys and for planning and evaluating association ...
Thomas Mailund, Mikkel H. Schierup, Christian N. S...
BMCBI
2010
164views more  BMCBI 2010»
13 years 5 months ago
Pan-genome sequence analysis using Panseq: an online tool for the rapid analysis of core and accessory genomic regions
Background: The pan-genome of a bacterial species consists of a core and an accessory gene pool. The accessory genome is thought to be an important source of genetic variability i...
Chad Laing, Cody Buchanan, Eduardo N. Taboada, Yon...