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» Power and sample size estimation in microarray studies
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BMCBI
2006
90views more  BMCBI 2006»
13 years 4 months ago
The PowerAtlas: a power and sample size atlas for microarray experimental design and research
Background: Microarrays permit biologists to simultaneously measure the mRNA abundance of thousands of genes. An important issue facing investigators planning microarray experimen...
Grier P. Page, Jode W. Edwards, Gary L. Gadbury, P...
BMCBI
2010
80views more  BMCBI 2010»
13 years 5 months ago
Power and sample size estimation in microarray studies
Background: Before conducting a microarray experiment, one important issue that needs to be determined is the number of arrays required in order to have adequate power to identify...
Wei-Jiun Lin, Huey-miin Hsueh, James J. Chen
BMCBI
2008
107views more  BMCBI 2008»
13 years 5 months ago
A mixture model approach to sample size estimation in two-sample comparative microarray experiments
Background: Choosing the appropriate sample size is an important step in the design of a microarray experiment, and recently methods have been proposed that estimate sample sizes ...
Tommy S. Jørstad, Herman Midelfart, Atle M....
BMCBI
2010
161views more  BMCBI 2010»
13 years 5 months ago
CGHpower: exploring sample size calculations for chromosomal copy number experiments
Background: Determining a suitable sample size is an important step in the planning of microarray experiments. Increasing the number of arrays gives more statistical power, but ad...
Ilari Scheinin, Jose A. Ferreira, Sakari Knuutila,...
BMCBI
2010
190views more  BMCBI 2010»
13 years 5 months ago
Sample size and statistical power considerations in high-dimensionality data settings: a comparative study of classification alg
Background: Data generated using `omics' technologies are characterized by high dimensionality, where the number of features measured per subject vastly exceeds the number of...
Yu Guo, Armin Graber, Robert N. McBurney, Raji Bal...