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BMCBI
2010
115views more  BMCBI 2010»
13 years 5 months ago
Assessment and optimisation of normalisation methods for dual-colour antibody microarrays
Background: Recent advances in antibody microarray technology have made it possible to measure the expression of hundreds of proteins simultaneously in a competitive dual-colour a...
Martin Sill, Christoph Schroder, Jörg D. Hohe...
BMCBI
2006
99views more  BMCBI 2006»
13 years 5 months ago
A proposed metric for assessing the measurement quality of individual microarrays
Background: High-density microarray technology is increasingly applied to study gene expression levels on a large scale. Microarray experiments rely on several critical steps that...
Kyoungmi Kim, Grier P. Page, T. Mark Beasley, Step...
BIOINFORMATICS
2005
72views more  BIOINFORMATICS 2005»
13 years 5 months ago
Use of within-array replicate spots for assessing differential expression in microarray experiments
Motivation. Spotted arrays are often printed with probes in duplicate or triplicate, but current methods for assessing differential expression are not able to make full use of the...
Gordon K. Smyth, Joëlle Michaud, Hamish S. Sc...
BMCBI
2006
154views more  BMCBI 2006»
13 years 5 months ago
An improved procedure for gene selection from microarray experiments using false discovery rate criterion
Background: A large number of genes usually show differential expressions in a microarray experiment with two types of tissues, and the p-values of a proper statistical test are o...
James J. Yang, Mark C. K. Yang
BMCBI
2006
126views more  BMCBI 2006»
13 years 5 months ago
OpWise: Operons aid the identification of differentially expressed genes in bacterial microarray experiments
Background: Differentially expressed genes are typically identified by analyzing the variation between replicate measurements. These procedures implicitly assume that there are no...
Morgan N. Price, Adam P. Arkin, Eric J. Alm