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» Pre-processing Agilent microarray data
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BMCBI
2011
12 years 8 months ago
Evaluating methods for ranking differentially expressed genes applied to MicroArray Quality Control data
Background: Statistical methods for ranking differentially expressed genes (DEGs) from gene expression data should be evaluated with regard to high sensitivity, specificity, and r...
Koji Kadota, Kentaro Shimizu
BMCBI
2007
105views more  BMCBI 2007»
13 years 4 months ago
Extended analysis of benchmark datasets for Agilent two-color microarrays
Background: As part of its broad and ambitious mission, the MicroArray Quality Control (MAQC) project reported the results of experiments using External RNA Controls (ERCs) on fiv...
Kathleen F. Kerr
BMCBI
2007
239views more  BMCBI 2007»
13 years 4 months ago
Pre-processing Agilent microarray data
Background: Pre-processing methods for two-sample long oligonucleotide arrays, specifically the Agilent technology, have not been extensively studied. The goal of this study is to...
Marianna Zahurak, Giovanni Parmigiani, Wayne Yu, R...
BMCBI
2010
108views more  BMCBI 2010»
13 years 4 months ago
Error, reproducibility and sensitivity : a pipeline for data processing of Agilent oligonucleotide expression arrays
Background: Expression microarrays are increasingly used to obtain large scale transcriptomic information on a wide range of biological samples. Nevertheless, there is still much ...
Benjamin Chain, Helen Bowen, John Hammond, Wilfrie...
BMCBI
2005
120views more  BMCBI 2005»
13 years 4 months ago
A microarray study of MPP+-treated PC12 Cells: Mechanisms of toxicity (MOT) analysis using bioinformatics tools
Background: This paper describes a microarray study including data quality control, data analysis and the analysis of the mechanism of toxicity (MOT) induced by 1-methyl-4-phenylp...
Zengjun Xu, Tucker A. Patterson, Jonathan D. Wren,...