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» Predicting Continuous Epitopes in Proteins
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BMCBI
2008
134views more  BMCBI 2008»
13 years 6 months ago
PEPOP: Computational design of immunogenic peptides
Background: Most methods available to predict protein epitopes are sequence based. There is a need for methods using 3D information for prediction of discontinuous epitopes and de...
Violaine Moreau, Cécile Fleury, Dominique P...
BMCBI
2007
92views more  BMCBI 2007»
13 years 6 months ago
Large-scale validation of methods for cytotoxic T-lymphocyte epitope prediction
Background: Reliable predictions of Cytotoxic T lymphocyte (CTL) epitopes are essential for rational vaccine design. Most importantly, they can minimize the experimental effort ne...
Mette V. Larsen, Claus Lundegaard, Kasper Lamberth...
BMCBI
2006
159views more  BMCBI 2006»
13 years 6 months ago
EpiJen: a server for multistep T cell epitope prediction
Background: The main processing pathway for MHC class I ligands involves degradation of proteins by the proteasome, followed by transport of products by the transporter associated...
Irini A. Doytchinova, Pingping Guan, Darren R. Flo...
NAR
2006
89views more  NAR 2006»
13 years 6 months ago
AlgPred: prediction of allergenic proteins and mapping of IgE epitopes
In this study a systematic attempt has been made to integrate various approaches in order to predict allergenic proteins with high accuracy. The dataset used for testing and train...
Sudipto Saha, G. P. S. Raghava
NAR
2008
101views more  NAR 2008»
13 years 6 months ago
PVS: a web server for protein sequence variability analysis tuned to facilitate conserved epitope discovery
We have developed PVS (Protein Variability Server), a web-based tool that uses several variability metrics to compute the absolute site variability in multiple protein-sequence al...
Maria Garcia-Boronat, Carmen M. Diez-Rivero, Ellis...