Motivation: Over 50% of human genes contain CpG islands in their 5'-regions. Methylation patterns of CpG islands are involved in tissue-specific gene expression and regulatio...
Fang Fang, Shicai Fan, Xuegong Zhang, Michael Q. Z...
— A DNA sequence can be described as a string composed of four symbols: A, T, C and G. Each symbol represents a chemically distinct nucleotide molecule. Combinations of two nucle...
Background: The substitution rates within different nucleotide contexts are subject to varying levels of bias. The most well known example of such bias is the excess of C to T (C ...
Alexander Y. Panchin, Sergey I. Mitrofanov, Andrei...