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IJCNN
2006
IEEE
13 years 10 months ago
Comparing Kernels for Predicting Protein Binding Sites from Amino Acid Sequence
— The ability to identify protein binding sites and to detect specific amino acid residues that contribute to the specificity and affinity of protein interactions has importan...
Feihong Wu
BMCBI
2006
95views more  BMCBI 2006»
13 years 4 months ago
Predicting DNA-binding sites of proteins from amino acid sequence
Background: Understanding the molecular details of protein-DNA interactions is critical for deciphering the mechanisms of gene regulation. We present a machine learning approach f...
Changhui Yan, Michael Terribilini, Feihong Wu, Rob...
BMCBI
2006
100views more  BMCBI 2006»
13 years 4 months ago
STAR: predicting recombination sites from amino acid sequence
Background: Designing novel proteins with site-directed recombination has enormous prospects. By locating effective recombination sites for swapping sequence parts, the probabilit...
Denis C. Bauer, Mikael Bodén, Ricarda Thier...
JIB
2006
78views more  JIB 2006»
13 years 4 months ago
Prediction of transcription factor binding to DNA using rule induction methods
In this study, we seek to develop a predictive model for finding the strength of binding between a particular transcription factor (TF) variant and a particular DNA target variant...
Mikael Huss, Karin Nordström
BMCBI
2010
95views more  BMCBI 2010»
13 years 4 months ago
An effective approach for identification of in vivo protein-DNA binding sites from paired-end ChIP-Seq data
Background: ChIP-Seq, which combines chromatin immunoprecipitation (ChIP) with high-throughput massively parallel sequencing, is increasingly being used for identification of prot...
Congmao Wang, Jie Xu, Dasheng Zhang, Zoe A. Wilson...