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» Predicting MHC class I epitopes in large datasets
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BMCBI
2008
100views more  BMCBI 2008»
13 years 5 months ago
Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen p
Background: T-cell epitopes that promiscuously bind to multiple alleles of a human leukocyte antigen (HLA) supertype are prime targets for development of vaccines and immunotherap...
Guanglan Zhang, Asif M. Khan, Kellathur N. Sriniva...
JCC
2007
82views more  JCC 2007»
13 years 5 months ago
Peptide reagent design based on physical and chemical properties of amino acid residues
: It has tremendous values for both drug discovery and basic research to develop a solid bioinformatical tool for guiding peptide reagent design. Based on the physical and chemical...
Qishi Du, Ri-Bo Huang, Yu-Tuo Wei, Cheng-Hua Wang,...
BMCBI
2011
12 years 9 months ago
HomPPI: A Class of Sequence Homology Based Protein-Protein Interface Prediction Methods
Background: Although homology-based methods are among the most widely used methods for predicting the structure and function of proteins, the question as to whether interface sequ...
Li C. Xue, Drena Dobbs, Vasant Honavar
LREC
2010
206views Education» more  LREC 2010»
13 years 6 months ago
Efficient Multilabel Classification Algorithms for Large-Scale Problems in the Legal Domain
In this paper we evaluate the performance of multilabel classification algorithms on the EUR-Lex database of legal documents of the European Union. On the same set of underlying d...
Eneldo Loza Mencía, Johannes Fürnkranz
WWW
2005
ACM
14 years 6 months ago
Towards autonomic web-sites based on learning automata
Autonomics or self-reorganization becomes pertinent for websites serving a large number of users with highly varying workloads. An important component of self-adaptation is to mod...
Pradeep S, Chitra Ramachandran, Srinath Srinivasa