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» Predicting altered pathways using extendable scaffolds
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IJBRA
2006
59views more  IJBRA 2006»
13 years 4 months ago
Predicting altered pathways using extendable scaffolds
: Many diseases, especially solid tumors, involve the disruption or deregulation of cellular processes. Most current work using gene expression and other high-throughput data, simp...
B. M. Broom, T. J. McDonnell, D. Subramanian
BMCBI
2010
183views more  BMCBI 2010»
13 years 4 months ago
Active learning for human protein-protein interaction prediction
Background: Biological processes in cells are carried out by means of protein-protein interactions. Determining whether a pair of proteins interacts by wet-lab experiments is reso...
Thahir P. Mohamed, Jaime G. Carbonell, Madhavi Gan...
BMCBI
2010
177views more  BMCBI 2010»
13 years 4 months ago
Modular composition predicts kinase/substrate interactions
Background: Phosphorylation events direct the flow of signals and metabolites along cellular protein networks. Current annotations of kinase-substrate binding events are far from ...
Yichuan Liu, Aydin Tozeren
ECSQARU
2007
Springer
13 years 11 months ago
Extending Classical Planning to the Multi-agent Case: A Game-Theoretic Approach
When several agents operate in a common environment, their plans may interfere so that the predicted outcome of each plan may be altered, even if it is composed of deterministic ac...
Ramzi Ben Larbi, Sébastien Konieczny, Pierr...
BMCBI
2005
223views more  BMCBI 2005»
13 years 4 months ago
Bioinformatics approaches for cross-species liver cancer analysis based on microarray gene expression profiling
Background: The completion of the sequencing of human, mouse and rat genomes and knowledge of cross-species gene homologies enables studies of differential gene expression in anim...
Hong Fang, Weida Tong, Roger Perkins, Leming M. Sh...