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BMCBI
2004
93views more  BMCBI 2004»
13 years 4 months ago
Predicting binding sites of hydrolase-inhibitor complexes by combining several methods
Background: Protein-protein interactions play a critical role in protein function. Completion of many genomes is being followed rapidly by major efforts to identify interacting pr...
Taner Z. Sen, Andrzej Kloczkowski, Robert L. Jerni...
ESANN
2006
13 years 5 months ago
Using sampling methods to improve binding site predictions
Currently the best algorithms for transcription factor binding site prediction are severely limited in accuracy. In previous work we combine random selection under-sampling with th...
Yi Sun, Mark Robinson, Rod Adams, Rene te Boekhors...
JIB
2006
78views more  JIB 2006»
13 years 4 months ago
Prediction of transcription factor binding to DNA using rule induction methods
In this study, we seek to develop a predictive model for finding the strength of binding between a particular transcription factor (TF) variant and a particular DNA target variant...
Mikael Huss, Karin Nordström
BMCBI
2007
148views more  BMCBI 2007»
13 years 4 months ago
fREDUCE: Detection of degenerate regulatory elements using correlation with expression
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...
Randy Z. Wu, Christina Chaivorapol, Jiashun Zheng,...
BIOINFORMATICS
2012
11 years 7 months ago
Epigenetic priors for identifying active transcription factor binding sites
Motivation Accurate knowledge of the genome-wide binding of transcription factors in a particular cell type or under a particular condition is necessary for understanding transcri...
Gabriel Cuellar-Partida, Fabian A. Buske, Robert C...