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» Predicting conserved protein motifs with Sub-HMMs
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BMCBI
2010
123views more  BMCBI 2010»
12 years 11 months ago
Predicting conserved protein motifs with Sub-HMMs
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
Kevin Horan, Christian R. Shelton, Thomas Girke
BMCBI
2008
96views more  BMCBI 2008»
13 years 4 months ago
MSDmotif: exploring protein sites and motifs
Background: Protein structures have conserved features
Adel Golovin, Kim Henrick
BMCBI
2008
123views more  BMCBI 2008»
13 years 4 months ago
A tree-based conservation scoring method for short linear motifs in multiple alignments of protein sequences
Background: The structure of many eukaryotic cell regulatory proteins is highly modular. They are assembled from globular domains, segments of natively disordered polypeptides and...
Claudia Chica, Alberto Labarga, Cathryn M. Gould, ...
IDEAL
2005
Springer
13 years 9 months ago
Exploiting Sequence Dependencies in the Prediction of Peroxisomal Proteins
Prediction of peroxisomal matrix proteins generally depends on the presence of one of two distinct motifs at the end of the amino acid sequence. PTS1 peroxisomal proteins have a we...
Mark Wakabayashi, John Hawkins, Stefan Maetschke, ...
BMCBI
2004
229views more  BMCBI 2004»
13 years 4 months ago
Automatic annotation of protein motif function with Gene Ontology terms
Background: Conserved protein sequence motifs are short stretches of amino acid sequence patterns that potentially encode the function of proteins. Several sequence pattern search...
Xinghua Lu, Chengxiang Zhai, Vanathi Gopalakrishna...