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BMCBI
2010
159views more  BMCBI 2010»
13 years 3 months ago
Predicting domain-domain interaction based on domain profiles with feature selection and support vector machines
Background: Protein-protein interaction (PPI) plays essential roles in cellular functions. The cost, time and other limitations associated with the current experimental methods ha...
Alvaro J. González, Li Liao
BMCBI
2011
12 years 10 months ago
DoBo: Protein domain boundary prediction by integrating evolutionary signals and machine learning
Background: Accurate identification of protein domain boundaries is useful for protein structure determination and prediction. However, predicting protein domain boundaries from a...
Jesse Eickholt, Xin Deng, Jianlin Cheng
NAR
2011
182views Computer Vision» more  NAR 2011»
12 years 6 months ago
PAIR: the predicted Arabidopsis interactome resource
The predicted Arabidopsis interactome resource (PAIR, http://www.cls.zju.edu.cn/pair/), comprised of 5990 experimentally reported molecular interactions in Arabidopsis thaliana to...
Mingzhi Lin, Xueling Shen, Xin Chen
BIBE
2007
IEEE
142views Bioinformatics» more  BIBE 2007»
13 years 10 months ago
An HV-SVM Classifier to Infer TF-TF Interactions Using Protein Domains and GO Annotations
—Interactions between transcription factors (TFs) are necessary for deciphering the complex mechanisms of transcription regulation in eukaryotes. In this paper, we proposed a nov...
Xiaoli Li, Jun-Xiang Lee, Bharadwaj Veeravalli, Se...
BMCBI
2005
155views more  BMCBI 2005»
13 years 3 months ago
Mining protein function from text using term-based support vector machines
Background: Text mining has spurred huge interest in the domain of biology. The goal of the BioCreAtIvE exercise was to evaluate the performance of current text mining systems. We...
Simon B. Rice, Goran Nenadic, Benjamin J. Stapley