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BMCBI
2004
93views more  BMCBI 2004»
13 years 5 months ago
Predicting binding sites of hydrolase-inhibitor complexes by combining several methods
Background: Protein-protein interactions play a critical role in protein function. Completion of many genomes is being followed rapidly by major efforts to identify interacting pr...
Taner Z. Sen, Andrzej Kloczkowski, Robert L. Jerni...
BMCBI
2006
133views more  BMCBI 2006»
13 years 5 months ago
Choosing negative examples for the prediction of protein-protein interactions
The protein-protein interaction networks of even well-studied model organisms are sketchy at best, highlighting the continued need for computational methods to help direct experim...
Asa Ben-Hur, William Stafford Noble
NAR
2011
257views Computer Vision» more  NAR 2011»
12 years 8 months ago
The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
An essential prerequisite for any systems-level understanding of cellular functions is to correctly uncover and annotate all functional interactions among proteins in the cell. To...
Damian Szklarczyk, Andrea Franceschini, Michael Ku...
BMCBI
2008
90views more  BMCBI 2008»
13 years 5 months ago
Ortholog-based protein-protein interaction prediction and its application to inter-species interactions
Background: The rapid growth of protein-protein interaction (PPI) data has led to the emergence of PPI network analysis. Despite advances in high-throughput techniques, the intera...
Sheng-An Lee, Chen-hsiung Chan, Chi-Hung Tsai, Jin...
NAR
2002
138views more  NAR 2002»
13 years 5 months ago
The KEGG databases at GenomeNet
The Kyoto Encyclopedia of Genes and Genomes (KEGG) is the primary database resource of the Japanese GenomeNet service (http://www.genome.ad.jp/) for understanding higher order fun...
Minoru Kanehisa, Susumu Goto, Shuichi Kawashima, A...