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BMCBI
2007
127views more  BMCBI 2007»
13 years 4 months ago
Predicting the phenotypic effects of non-synonymous single nucleotide polymorphisms based on support vector machines
Background: Human genetic variations primarily result from single nucleotide polymorphisms (SNPs) that occur approximately every 1000 bases in the overall human population. The no...
Jian Tian, Ningfeng Wu, Xuexia Guo, Jun Guo, Juhua...
BMCBI
2008
99views more  BMCBI 2008»
13 years 4 months ago
Exhaustive prediction of disease susceptibility to coding base changes in the human genome
Background: Single Nucleotide Polymorphisms (SNPs) are the most abundant form of genomic variation and can cause phenotypic differences between individuals, including diseases. Ba...
Vinayak Kulkarni, Mounir Errami, Robert Barber, Ha...
IJCNN
2006
IEEE
13 years 10 months ago
P-SVM Variable Selection for Discovering Dependencies Between Genetic and Brain Imaging Data
— The joint analysis of genetic and brain imaging data is the key to understand the genetic underpinnings of brain dysfunctions in several psychiatric diseases known to have a st...
Johannes Mohr, Imke Puis, Jana Wrase, Sepp Hochrei...