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BMCBI
2008
78views more  BMCBI 2008»
13 years 5 months ago
Evaluation of time profile reconstruction from complex two-color microarray designs
Background: As an alternative to the frequently used "reference design" for two-channel microarrays, other designs have been proposed. These designs have been shown to b...
Ana C. Fierro, Raphael Thuret, Kristof Engelen, Gi...
PR
2008
154views more  PR 2008»
13 years 5 months ago
Data-driven decomposition for multi-class classification
This paper presents a new study on a method of designing a multi-class classifier: Data-driven Error Correcting Output Coding (DECOC). DECOC is based on the principle of Error Cor...
Jie Zhou, Hanchuan Peng, Ching Y. Suen
BMCBI
2007
128views more  BMCBI 2007»
13 years 5 months ago
Model order selection for bio-molecular data clustering
Background: Cluster analysis has been widely applied for investigating structure in bio-molecular data. A drawback of most clustering algorithms is that they cannot automatically ...
Alberto Bertoni, Giorgio Valentini
BMCBI
2010
105views more  BMCBI 2010»
13 years 5 months ago
Effects of scanning sensitivity and multiple scan algorithms on microarray data quality
Background: Maximizing the utility of DNA microarray data requires optimization of data acquisition through selection of an appropriate scanner setting. To increase the amount of ...
Andrew Williams, Errol M. Thomson
BMCBI
2007
159views more  BMCBI 2007»
13 years 5 months ago
sIR: siRNA Information Resource, a web-based tool for siRNA sequence design and analysis and an open access siRNA database
Background: RNA interference has revolutionized our ability to study the effects of altering the expression of single genes in mammalian (and other) cells through targeted knockdo...
Jyoti K. Shah, Harold R. Garner, Michael A. White,...