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BMCBI
2007
126views more  BMCBI 2007»
13 years 5 months ago
High-throughput identification of interacting protein-protein binding sites
Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...
Jo-Lan Chung, Wei Wang, Philip E. Bourne
BMCBI
2006
159views more  BMCBI 2006»
13 years 5 months ago
Prediction of protein continuum secondary structure with probabilistic models based on NMR solved structures
Background: The structure of proteins may change as a result of the inherent flexibility of some protein regions. We develop and explore probabilistic machine learning methods for...
Mikael Bodén, Zheng Yuan, Timothy L. Bailey
BMCBI
2006
112views more  BMCBI 2006»
13 years 5 months ago
Protein disorder prediction by condensed PSSM considering propensity for order or disorder
Background: More and more disordered regions have been discovered in protein sequences, and many of them are found to be functionally significant. Previous studies reveal that dis...
Chung-Tsai Su, Chien-Yu Chen, Yu-Yen Ou
AO
2005
147views more  AO 2005»
13 years 5 months ago
Domain modelling and NLP: Formal ontologies? Lexica? Or a bit of both?
There are a number of genuinely open questions concerning the use of domain models in nlp. It would be great if contributors to Applied Ontology could help addressing them rather ...
Massimo Poesio
INFORMS
1998
100views more  INFORMS 1998»
13 years 5 months ago
Feature Selection via Mathematical Programming
The problem of discriminating between two nite point sets in n-dimensional feature space by a separating plane that utilizes as few of the features as possible, is formulated as a...
Paul S. Bradley, Olvi L. Mangasarian, W. Nick Stre...