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» Probabilistic Expression Analysis on Manifolds
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BMCBI
2008
128views more  BMCBI 2008»
13 years 5 months ago
Finding sequence motifs with Bayesian models incorporating positional information: an application to transcription factor bindin
Background: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (T...
Nak-Kyeong Kim, Kannan Tharakaraman, Leonardo Mari...
ENTCS
2008
103views more  ENTCS 2008»
13 years 5 months ago
Distributed Markovian Bisimulation Reduction aimed at CSL Model Checking
The verification of quantitative aspects like performance and dependability by means of model checking has become an important and vivid area of research over the past decade. An ...
Stefan Blom, Boudewijn R. Haverkort, Matthias Kunt...
BMCBI
2006
130views more  BMCBI 2006»
13 years 5 months ago
An interactive visualization tool to explore the biophysical properties of amino acids and their contribution to substitution ma
Background: Quantitative descriptions of amino acid similarity, expressed as probabilistic models of evolutionary interchangeability, are central to many mainstream bioinformatic ...
Blazej Bulka, Marie desJardins, Stephen J. Freelan...
BMCBI
2007
154views more  BMCBI 2007»
13 years 5 months ago
Inferring biological networks with output kernel trees
Background: Elucidating biological networks between proteins appears nowadays as one of the most important challenges in systems biology. Computational approaches to this problem ...
Pierre Geurts, Nizar Touleimat, Marie Dutreix, Flo...
BMCBI
2007
215views more  BMCBI 2007»
13 years 5 months ago
Learning causal networks from systems biology time course data: an effective model selection procedure for the vector autoregres
Background: Causal networks based on the vector autoregressive (VAR) process are a promising statistical tool for modeling regulatory interactions in a cell. However, learning the...
Rainer Opgen-Rhein, Korbinian Strimmer