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BMCBI
2010
113views more  BMCBI 2010»
13 years 4 months ago
Probabilistic Principal Component Analysis for Metabolomic Data
Background: Data from metabolomic studies are typically complex and high-dimensional. Principal component analysis (PCA) is currently the most widely used statistical technique fo...
Gift Nyamundanda, Lorraine Brennan, Isobel Claire ...
BMCBI
2010
112views more  BMCBI 2010»
13 years 4 months ago
The MetabolomeExpress Project: enabling web-based processing, analysis and transparent dissemination of GC/MS metabolomics datas
Background: Standardization of analytical approaches and reporting methods via community-wide collaboration can work synergistically with web-tool development to result in rapid c...
Adam J. Carroll, Murray R. Badger, A. Harvey Milla...
CSB
2005
IEEE
141views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Joint Genomic and Metabolomic Analysis of Toxic Dose-Response Experiments
A methodology has been implemented for analyzing microarray and NMR spectral data obtained from the same set of toxic-exposure dose-response experiments. The NMR spectra additiona...
Gary L. Jahns, Nicholas J. DelRaso, Mark P. Westri...
BMCBI
2007
106views more  BMCBI 2007»
13 years 4 months ago
Improved classification accuracy in 1- and 2-dimensional NMR metabolomics data using the variance stabilising generalised logari
Background: Classifying nuclear magnetic resonance (NMR) spectra is a crucial step in many metabolomics experiments. Since several multivariate classification techniques depend up...
Helen M. Parsons, Christian Ludwig, Ulrich L. G&uu...
KDD
2006
ACM
115views Data Mining» more  KDD 2006»
14 years 4 months ago
Supervised probabilistic principal component analysis
Principal component analysis (PCA) has been extensively applied in data mining, pattern recognition and information retrieval for unsupervised dimensionality reduction. When label...
Shipeng Yu, Kai Yu, Volker Tresp, Hans-Peter Krieg...