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» Probe set filtering increases correlation between Affymetrix...
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BMCBI
2010
193views more  BMCBI 2010»
13 years 4 months ago
Probe set filtering increases correlation between Affymetrix GeneChip and qRT-PCR expression measurements
Background: Affymetrix GeneChip microarrays are popular platforms for expression profiling in two types of studies: detection of differential expression computed by p-values of t-...
Jakub Mieczkowski, Magdalena E. Tyburczy, Michal D...
BMCBI
2005
144views more  BMCBI 2005»
13 years 4 months ago
Redefinition of Affymetrix probe sets by sequence overlap with cDNA microarray probes reduces cross-platform inconsistencies in
Background: Comparison of data produced on different microarray platforms often shows surprising discordance. It is not clear whether this discrepancy is caused by noisy data or b...
Scott L. Carter, Aron C. Eklund, Brigham H. Mecham...
BMCBI
2007
160views more  BMCBI 2007»
13 years 4 months ago
Establishing a major cause of discrepancy in the calibration of Affymetrix GeneChips
Background: Affymetrix GeneChips are a popular platform for performing whole-genome experiments on the transcriptome. There are a range of different calibration steps, and users a...
Andrew P. Harrison, Caroline E. Johnston, Christin...
BMCBI
2007
97views more  BMCBI 2007»
13 years 4 months ago
A verification protocol for the probe sequences of Affymetrix genome arrays reveals high probe accuracy for studies in mouse, hu
Background: The Affymetrix GeneChip technology uses multiple probes per gene to measure its expression level. Individual probe signals can vary widely, which hampers proper interp...
Rudi Alberts, Peter Terpstra, Menno Hardonk, Leoni...
BMCBI
2006
131views more  BMCBI 2006»
13 years 4 months ago
Hybridization interactions between probesets in short oligo microarrays lead to spurious correlations
Background: Microarrays measure the binding of nucleotide sequences to a set of sequence specific probes. This information is combined with annotation specifying the relationship ...
Michal J. Okoniewski, Crispin J. Miller