7 search results - page 1 / 2 » ProfNet, a method to derive profile-profile alignment scorin... |
BMCBI
2005
13 years 4 months ago
2005
Background: Profile-profile methods have been used for some years now to detect and align homologous proteins. The best such methods use information from the background distributi...
BMCBI
2006
13 years 4 months ago
2006
Background: Protein sequence alignment is one of the basic tools in bioinformatics. Correct alignments are required for a range of tasks including the derivation of phylogenetic t...
BMCBI
2005
13 years 4 months ago
2005
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
BMCBI
2006
13 years 4 months ago
2006
Background: Several entropy-based methods have been developed for scoring sequence conservation in protein multiple sequence alignments. High scoring amino acid positions may corr...
BMCBI
2010
13 years 4 months ago
2010
Background: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represent...