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» Progressive multiple alignment with constraints
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RECOMB
1997
Springer
13 years 8 months ago
Progressive multiple alignment with constraints
A progressive alignment algorithm produces a multi-alignment of a set of sequences by repeatedly aligning pairs of sequences and/or previously generated alignments. We describe a ...
Gene Myers, Sanford Selznick, Zheng Zhang 0004, We...
BMCBI
2007
153views more  BMCBI 2007»
13 years 4 months ago
Can Clustal-style progressive pairwise alignment of multiple sequences be used in RNA secondary structure prediction?
Background: In ribonucleic acid (RNA) molecules whose function depends on their final, folded three-dimensional shape (such as those in ribosomes or spliceosome complexes), the se...
Amelia B. Bellamy-Royds, Marcel Turcotte
BMCBI
2007
107views more  BMCBI 2007»
13 years 4 months ago
Progressive multiple sequence alignments from triplets
Motivation: The quality of progressive sequence alignments strongly depends on the accuracy of the individual pairwise alignment steps since gaps that are introduced at one step c...
Matthias Kruspe, Peter F. Stadler
CP
2003
Springer
13 years 9 months ago
A SAT-Based Approach to Multiple Sequence Alignment
Multiple sequence alignment is a central problem in Bioinformatics. A known integer programming approach is to apply branch-and-cut to exponentially large graph-theoretic models. T...
Steven David Prestwich, Desmond G. Higgins, Orla O...
BIOCOMP
2006
13 years 5 months ago
PAC: Progressive Alignment with Consensus Sequences
Computation of multiple sequence alignments is one of the major open problems in computational molecular biology. The purpose of this study was to provide a new method, PAC (Progre...
Ke Liu, Mansur H. Samadzadeh