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» Properties and identification of antibiotic drug targets
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BMCBI
2010
117views more  BMCBI 2010»
13 years 4 months ago
Properties and identification of antibiotic drug targets
Background: We analysed 48 non-redundant antibiotic target proteins from all bacteria, 22 antibiotic target proteins from E. coli only and 4243 non-drug targets from E. coli to id...
Tala Bakheet, Andrew J. Doig
BMCBI
2007
107views more  BMCBI 2007»
13 years 4 months ago
Prediction of potential drug targets based on simple sequence properties
Background: During the past decades, research and development in drug discovery have attracted much attention and efforts. However, only 324 drug targets are known for clinical dr...
Qingliang Li, Luhua Lai
NAR
2011
260views Computer Vision» more  NAR 2011»
12 years 7 months ago
ASD: a comprehensive database of allosteric proteins and modulators
Allostery is the most direct, rapid and efficient way of regulating protein function, ranging from the control of metabolic mechanisms to signaltransduction pathways. However, an ...
Zhimin Huang, Liang Zhu, Yan Cao, Geng Wu, Xinyi L...